Diclofenac for acute pain in children

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Population pharmacokinetics of oral diclofenac for acute pain in children.

AIMS To develop a population pharmacokinetic model for a new diclofenac suspension (50 mg 5 ml(-1)) in adult volunteers and paediatric patients, and recommend a dose for acute pain in children. METHODS Blood samples were drawn at the start and end of surgery, and on removal of the venous cannula from 70 children (aged 1 to 12 years, weight 9 to 37 kg) who received a preoperative oral 1 mg kg(...

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Comparative Effect of Cinnamon Essential Oil, Diclofenac and Morphine on Acute and Chronic Pain in Mice

Backgrounds and Aims: Cinnamomum Zeylanicum is a medicinal herb used in Iranian traditional medicine as an analgesic spice, which its analgesic effect has been experimentally confirmed. Thus, this study was conducted to compare the antinociceptive effect of cinnamon essential oil (CEO) with those of Morphine and Diclofenac in mice. Materials and Methods: 80 male albino mice were selected and...

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Acute pain management in children

The greatest advance in pediatric pain medicine is the recognition that untreated pain is a significant cause of morbidity and even mortality after surgical trauma. Accurate assessment of pain in different age groups and the effective treatment of postoperative pain is constantly being refined; with newer drugs being used alone or in combination with other drugs continues to be explored. Severa...

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Acute Abdominal Pain in Children.

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ژورنال

عنوان ژورنال: Cochrane Database of Systematic Reviews

سال: 2015

ISSN: 1465-1858

DOI: 10.1002/14651858.cd005538.pub3